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March-April 2003
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Fat brains

PRODUCT WATCH

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Skin deep
Cosmetics have increasingly been under scrutiny. The latest threat comes from a probable carcinogen and a known endocrine disruptor — phthalate. Three environmental and advocacy groups of the US found that eighty per cent of the 34 cosmetic products tested by them had phthalate. The Environmental Working Group, Coming Clean and Health Care Without Harm conducted the study.

Perfumes, body creams and nail polishes have been found to be laced with phthalates, which is used as a plastic softener and is added to cosmetics, toys, food wraps and paint.

When added to nail polish, phthalates helps them be chip resistant. Phthalates impart flexibility to thin films for mascara. It has the ability to make lotions penetrate deeper into the skin. In perfumes, phthalates keep the fragrance for longer periods. Branded perfumes have been found to contain 28,000 phthalates per million parts. Studies done on animals have demonstrated that phthalates damage the liver, kidneys, lungs, and reproductive system (causing infertility), and also harm the developing foetus. Whereas exposure of women to phthalates occurs through cosmetics, men have been found to be more vulnerable to the chemicals since they can be absorbed through the skin, inhaled as fumes, or ingested through contaminated food. Exposure of men to phthalates is known to cause atrophy of the testicles (hypospadias), and also damage the prostate gland.

Though alternatives to phthalates are readily available to the industry it is still the first preference for any type of cosmetic or beauty product. Choosing a phthalate-free cosmetic product becomes difficult for the consumer in the absence of any appropriate labelling outside the packaging.

The growing epidemic of obesity in America has different States formulating new healthy policies. More than 60 per cent of American adults and 13 per cent of children and adolescents are obese. Lax policies on fast food, which is usually, junk, high on fat content and almost zero in nutritive value aids the rise in the obesity epidemic sweeping across America. Almost 43 per cent of elementary schools, 74 per cent of middle schools and all high schools have vending machines offering carbonated soft drinks. Fast food like McDonald's is available in more than 20 per cent of schools at all levels. Schools get payoff from the coke companies and the fast food joints in terms of sports uniforms and scoreboards, which helps schools cut down on their education budgets. California in the meantime has banned the sale of soda and junk food in elementary schools and has limited their sale in middle school. In Tennessee and Wisconsin, it was the parents protests that made school districts refuse to sign contracts with soft-drink vendors.

p8_1.jpg (11517 bytes)Worried nutritionists say that it is time that the country redesigns its nutrition policies to improve dietary health. The rate of Type II diabetes in New York City is today 8 per cent, double than what it was in 1994. The increase has been attributed to people who eat much but exercise little. Growing evidence now suggests that fat people are actually victims of the type of food sold in fast-food outlets. These outlets sell hazardous products without providing any sort of health warnings that could be expected on these goods. Informing consumers properly is one of the key issues today in determining better health policies. Biologists are now putting forth the theory that the high sugar content in these fast foods may be triggering a physiological reaction which may be muting the hormonal signals which tell the brain when to stop eating. Leptin, which is continuously secreted by fat cells and whose level in the bloodstream indicates the status of the body's fat reserves, may become resistant in people who eat more of junk food. "The fatter a person becomes the more resistant they will be to the effects of leptin and the harder it is to reverse those effects", says physiologist Luciano Rossetti of the Albert Einstein College of Medicine in New York City, USA. Neurobiologist Sarah Leibowitz of the Rockefeller University in New York City is of the opinion that early exposures to fatty food can very well reconfigure children's bodies so that they always choose fatty foods. Foods high in sugar content can set up a cycle of instant satiation followed by a plunge in blood sugar, which leads to a natural desire for another snack. Fast food could well turn out to be as addictive as perhaps nicotine and cocaine.

Chlorinated water
C Villanueva et al in the study titled: "Meta-analysis of studies on individual consumption of chlorinated drinking water and bladder cancer" show that long term consumption of chlorinated drinking water is associated with risk of bladder cancer, particularly in men. It was observed that for a vast majority of population of industrialised countries exposed to chlorinated byproducts for long periods, the risks would be higher. In India, the situation is different because of the interplay of economics and public health. Chlorine is used to treat water and in the absence of any disinfection, there would be a high risk of biological diseases. On a risk scale, diseases and fatality due to biological contamination of water is far higher than that of bladder cancer. Chlorine provides what is called as 'residual' disinfection to protect against the biological contamination. This property is not provided by any available substitute like ozone or ultraviolet (UV). Till today, even in the US and Europe, 99 per cent of municipal water is chlorinated. Unless there are other viable alternatives in terms of affordability and easy applicability, chlorine will continue to be used widely.

E-mail: kogenvinas@imim.es

p9.jpg Mercury babies
A two-year long study carried out on 1,057 infants by Professor Fok Fai Tai of the department of pediatrics, The Chinese Unit of Hong Kong, has found that a quarter of infants in Hong Kong have excessive mercury in their blood. Excess of mercury is known to cause mental retardation. Pregnant mothers, who consume too much fish, readily pass on the methylmercury into the foetal circulation system. This methylmercury then gets deposited in the foetal brain, and may lead to stillbirth, cerebral palsy, mental retardation, speech delay, poor control of chewing, salivation and swallowing.

In as many as 24.7 per cent of the infants, cord blood mercury concentrations were found to be of over 61 nanomol/litre, which is the upper allowable limit. Three per cent had blood mercury concentrations of over 100 nanomol/litre. Says Professor Fok Tai Fai, "Eating too much fish by the mother during pregnancy is the major factor in elevating the blood mercury level of the foetus." It just takes four days for methylmercury to be readily absorbed into the blood after ingestion and to get distributed to all tissues of the body.

In adults, mercury poisoning causes personality changes, nervousness, irritability, fatigue, insomnia, headache, loss of memory, hearing and vision and even renal failure.

E-mail: taifaifok@cuhk.ed.hk

Age and cancer
The US government finally accept that children are more vulnerable to the effects of certain carcinogens than adults. The US Environment Protection Agency's (EPA) draft for new guidelines for cancer risk assessment considers children aged two and younger to have 10 times the cancer risk of adults when exposed to mutagenic carcinogens. These carcinogens such as arsenic, benzene, formaldehyde, mutagen X, brominated organics and polycyclic aromatic hydrocarbons are known to cause cancer through direct damage to the DNA. Children between the ages of 2-15 years have three times the risk of adults.

p9_2.jpg (3567 bytes)The guidelines have been updated after 1986. The new guidelines take into consideration not only the amount of dosage exposure of toxic chemical but also considers factors like the time children spend outside and their unique vulnerability with regards to their eating, drinking and breathing in greater proportion to their body weights than adults. For the first time, the risk assessment studies have incorporated elements of both, biology and lifestyle.

 

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